Managing moderately severe depression
Depression is very common, but also very treatable. With the right care — including therapy, medication, or a combination of both — most people with depression feel better and enjoy life more.
Individual and group therapy
Therapy can help you explore your feelings and understand your thoughts, behaviors, and emotions. It can also guide you in taking proactive steps to feel better.
Learn more about therapy and other care options.
Antidepressants change the balance of chemicals in the brain that often cause depression. You may need to try several antidepressants before you find the one that works best for you. Talk to your doctor about whether antidepressants might be right for you.
Common medications for depression include:
- Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine (Prozac) and sertraline (Zoloft).
- Serotonin norepinephrine reuptake inhibitors (SNRIs), such as venlafaxine (Effexor), venlafaxine SR (Effexor XR), and duloxetine (Cymbalta).
- Other antidepressants, such as bupropion (Wellbutrin, Wellbutrin SR), mirtazapine (Remeron), and trazodone (Desyrel).
Take the self-assessment
Depression is a real – and common – medical condition that can affect your mind, body, and spirit. Take this self-assessment to see if you have any symptoms of depression.
Reviewed by Nolan Thompson, MD, April 2019.