In the U.S., most people with mpox develop a rash. It usually starts as a red area that turns into pimples and blisters before scabbing. Before the rash starts, some people also experience fever, chills, and fatigue.
The rash is often only in the genital area and thighs. But there have been cases where the rash is on the face, hands, and arms. It’s important to keep the rash covered around other people whenever possible.