Brenham Hughes, MD

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My specialty:
Internal Medicine

My affiliation:
Kaiser Permanente provider

I speak: English

My gender: Male

Where I practice

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About me

I grew up in the foothills of western North Carolina, which is known for its small towns and scenic mountain landscapes. I earned both my undergraduate and medical degrees at East Carolina University, and then completed my internship and residency at the University of South Carolina School of Medicine Greenville. I’m board certified in internal medicine and pediatrics  and a member of the American Medical Association, the American College of Physicians, and the American Academy of Pediatrics.

 

About my practice

 

As a physician, I’m grateful for the chance to combine my two passions – science and teaching. Medicine allows me to educate people in meaningful, practical ways, helping them build healthier lives and reach their fullest potential.

 

I’m drawn to the wide-ranging challenges and rewards of both internal medicine and pediatrics. Children inspire me daily with their resilience and joy, while my adult patients offer rich opportunities to connect, learn from their experiences, and share in their personal journeys. Those relationships are at the heart of why I love this work.

 

During residency, I led a quality improvement project that helped families learn to cook with accessible, everyday foods and practice mindful eating. My clinical interests include caring for adolescents with complex needs, supporting LGBTQIA+ health, and advancing medical education.

 

How I thrive

 

I enjoy hobbies that keep both my mind and body active – running, tennis, snorkeling, rowing, hot yoga, board games, crafting, reading, and tackling complicated puzzles. I also love spending time with my goldendoodle. Some of my favorite moments are the simple ones: taking evening walks on the beach with my husband, trying new restaurants together, and going to concerts.

My office

Referral requirements

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My training, certifications & licensing

Medical school

The Brody School of Medicine at East Carolina University
Greenville , NC

Board certification

Internal Medicine

American Board of Internal Medicine

Pediatrics

American Board of Pediatrics

To verify board certification for an individual practitioner, please visit the American Board of Medical Specialties, the American Medical Association, or the American Osteopathic Association websites.

Medical training

Residency

Internal Medicine/ Pediatrics

Prisma Health
Greenville , SC

Joined Permanente Medical Group

2025

Provider ID

23772

My hospitals

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This page was last updated on: 02/21/2026