Miglustat - oral
Miglustat - oral
Miglustat is used for the long-term treatment of a certain rare genetic problem (Gaucher's disease). It works by decreasing the amount of a certain natural fatty substance (glucosylceramide) that builds up due to this condition. This can help improve symptoms of Gaucher's disease, such as tiredness, pain in the joints/bones, and a swollen liver or spleen.
Read the Patient Information Leaflet if available from your pharmacist before you start taking miglustat and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually 3 times a day. The dosage is based on your medical condition and response to treatment.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
Tell your doctor if your condition does not improve or if it worsens.
Nausea, vomiting, stomach/abdominal pain, gas, diarrhea, weight loss, headache, muscle cramps, dizziness, or weakness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
To reduce diarrhea, your doctor may tell you to take miglustat between meals, recommend that you change your diet to avoid high-carbohydrate foods, or prescribe a drug (such as loperamide) to treat diarrhea. Talk to your doctor or pharmacist for more details.
Tell your doctor right away if you have any serious side effects, including:
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
In the US -
Before taking miglustat, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Do not share this medication with others.
Laboratory and/or medical tests (such as nerve function, kidney function, liver/spleen measurements, complete blood count including platelets) should be performed periodically to monitor your progress or check for side effects.
Information last revised October 2018.
Copyright(c) 2018 First Databank, Inc.