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Impaired immune system

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The immune system is the body's natural defense system that helps fight infections. An impaired immune system does not work properly and can't effectively protect a person against infection.

Some conditions and medicines weaken or impair the immune system. These may include:

  • Substance use disorders or problems caused by quitting their use (withdrawal).
  • Certain diseases or conditions. Diabetes, cancer, HIV/AIDS, or conditions in which the body mistakenly identifies its own tissues as harmful (autoimmune disorders) are some examples.
  • Chemotherapy or radiation therapy.
  • Some medicines, such as corticosteroids or those taken to suppress the immune system after an organ transplant.
  • Surgery to remove the spleen (splenectomy).

Current as of: September 25, 2023

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

Current as of: September 25, 2023

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

The Health Encyclopedia contains general health information. Not all treatments or services described are covered benefits for Kaiser Permanente members or offered as services by Kaiser Permanente. For a list of covered benefits, please refer to your Evidence of Coverage or Summary Plan Description. For recommended treatments, please consult with your health care provider.