Angiotensin receptor neprilysin inhibitors (ARNIs) are a type of medicine that relaxes blood vessels and lowers your blood pressure. It makes it easier for blood to flow through the vessels. It can make it easier for your heart to pump blood.
This medicine may be used to treat heart failure. It may help reduce your symptoms and lower the risk of serious problems that would need to be treated in the hospital.
Examples
An example of an ARNI is sacubitril with valsartan (Entresto).
Possible side effects
All medicines can cause side effects.
Side effects of ARNI medicines include:
Feeling lightheaded or dizzy.
Low blood pressure. You may feel dizzy and weak.
High potassium levels.
Cough.
Kidney problems.
Swelling of your lips, tongue, or face. Rarely, swelling becomes severe and makes it hard to breathe. In this case, you may need treatment right away.
You may have other side effects or reactions not listed here. Check the information that comes with your medicine or ask your doctor or pharmacist about the side effects of each medicine you take.
What to know about taking this medicine
Be safe with medicines. Take your medicines exactly as prescribed. Contact your doctor if you think you are having a problem with your medicine or if you missed a dose of a medicine.
These medicines can cause an allergic reaction. This can cause a little swelling. Or it can cause red bumps on your skin that hurt. In rare cases, the swelling may make it hard for you to breathe. If this happens, you may need treatment right away.
Do not take this medicine if you are pregnant, breastfeeding, or planning to become pregnant.
Taking some medicines together can cause problems. Tell your doctor or pharmacist all the medicines you take. This includes other prescription medicines, over-the-counter medicines, vitamins, supplements, and herbal remedies.
You may need regular blood and urine tests to see if the medicines are causing any problems.
Clinical Review Board All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.
Clinical Review Board All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.
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The Health Encyclopedia contains general health information. Not all treatments or services described are covered benefits for Kaiser Permanente members or offered as services by Kaiser Permanente. For a list of covered benefits, please refer to your Evidence of Coverage or Summary Plan Description. For recommended treatments, please consult with your health care provider.
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