verteporfin 15 mg intravenous solution

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Medication name

Generic name:
Verteporfin - injection

Pronunciation
(VER-te-POR-fin)

Brand name(s)
Visudyne

Uses

Verteporfin is used along with laser light treatment to treat certain serious eye conditions (such as macular degeneration, pathologic myopia, ocular histoplasmosis). It is used to help prevent decreased vision and blindness. After you have received the injection of verteporfin, your doctor will use laser light treatment on the affected eye(s). The laser light will change the drug to a form that works by damaging only those cells that cause the serious eye problem.

How to use

This medication is given by injection into a vein by a health care professional as directed by your doctor. The dosage is based on your body size and response to treatment.

Your doctor will treat your affected eye with laser light about 15 minutes after you receive this medication. If you have any questions about the treatment, consult your doctor.

Wear a wristband for 5 days after receiving this drug to notify other health care professionals that you have received this drug and to remind you to avoid bright lights (such as halogen lights) and direct sunlight. However, do not stay in totally dark areas after treatment. You should expose your skin to regular indoor/indirect light because doing so will help stop any drug in your skin from causing damage to skin cells. If any of the information is unclear, consult your doctor. (See also Precautions section.)

Side effects

Injection site reactions (such as pain, redness, irritation, swelling), headache, tiredness, or blurred vision may occur. If any of these effects last or get worse, tell your doctor promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

  • chest pain
  • fainting
  • eye pain
  • sudden change in vision
  • severe pain/swelling at injection site

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • flushing
  • severe dizziness
  • trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using this medication, tell your doctor or pharmacist if you are allergic to verteporfin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • a certain metabolic disorder (porphyria)
  • liver disease

This medication will make you more sensitive to the sun and to bright indoor lights. Avoid sun exposure, halogen lights, high-powered indoor lighting used in operating rooms/dental offices, tanning booths, and sunlamps for at least 5 days after receiving this medication. Wear protective clothing and dark sunglasses when outdoors. Sunscreens will not provide protection.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). It is recommended that you avoid surgery/dental procedures for at least 5 days after receiving a dose of verteporfin.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk and may have undesirable effects on a nursing infant. Breastfeeding is not recommended while using this medication. Consult your doctor before breastfeeding.

Drug interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.

Notes

Your doctor will schedule periodic eye exams to monitor your progress or check for side effects.

Missed dose

Not applicable.

Storage

Not applicable. This medication is given in a clinic and will not be stored at home.

Important note

HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Information last revised May 2024.

Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc., 2019. This copyrighted material has been downloaded from a licensed data provider.

The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment.