Tigan 100 mg/mL intramuscular solution

Generic name:
Trimethobenzamide - injection

Pronunciation
(trye-METH-oh-BEN-za-mide)

Brand name(s)
Tigan

This medication is used to treat nausea and vomiting that can happen due to surgery or certain stomach/intestinal problems (such as gastroenteritis). Treating vomiting quickly can keep you from getting dehydrated. Trimethobenzamide belongs to a class of drugs known as antiemetics. It works by stopping the signals in the brain that cause vomiting.

Trimethobenzamide injection must not be used by children.

This medication is given by injection into a large muscle of the buttock by a health care professional. It is given as directed by your doctor, usually 3 to 4 times a day as needed. This medication should not be injected into a vein. The dosage is based on your medical condition and response to treatment.

Tell your doctor if your condition lasts or gets worse.

Diarrhea, headache, dizziness, drowsiness, blurred vision, muscle cramps, or pain/stinging/burning/redness at the injection site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

• confusion
• muscle spasms
• unusual uncontrolled movements (especially of the face, mouth, tongue, arms, or legs)
• shaking (tremor)
• restlessness
• drooling
• severe arching of the back
• mouth sores
• unusual bleeding/bruising
• mental/mood changes (such as depression)
• yellowing eyes/skin
• dark urine

Get medical help right away if you have any very serious side effects, including:

• seizures

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before using trimethobenzamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

• high fever
• kidney problems
• stomach/intestinal problems (such as appendicitis)
• swelling/disease of the brain (encephalitis/encephalopathy)
• dehydration
• electrolyte imbalance

This drug may make you dizzy or drowsy or cause blurred vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Older adults may be more sensitive to the side effects of this drug, especially unusual uncontrolled movements and shaking.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.

Do not share this medication with others.

Lab and/or medical tests (such as complete blood counts, liver function) should be done while you are using this medication. Keep all medical and lab appointments.

Not applicable.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.