Lugols 5 % oral solution

Generic name:
Iodine, strong - oral

Pronunciation
(EYE-oh-dine)

This medication contains iodine and potassium iodide. It is used along with antithyroid medicines to prepare the thyroid gland for surgical removal and to treat certain overactive thyroid conditions (hyperthyroidism, thyroid storm). It works by shrinking the size of the thyroid gland and by decreasing the amount of thyroid hormones the body makes.

This medication may also be used to protect the thyroid gland after radioactive iodine treatment or in a radiation exposure emergency. In such cases, this product blocks the thyroid gland from absorbing radioactive iodine, protecting it from damage and reducing the risk of thyroid cancer. In a radiation exposure emergency, use this medication along with other emergency measures that will be recommended to you by public health and safety officials (such as finding safe shelter, evacuation, controlling food supply).

This medication may also be used for other conditions as determined by your doctor (such as treatment of iodine deficiency).

Take this medication by mouth as directed. Use the dropper that comes with the bottle to measure the correct dose. To improve the taste, mix the dose in a full glass (8 ounces or 240 milliliters) of water, milk, formula, or juice before taking. To decrease stomach upset, take this medication after meals or with food.

Dosage is based on your medical condition and response to treatment. Do not increase your dose, take it more often, or take it for longer than prescribed or recommended because of the increased risk of side effects.

In a radiation emergency, take this drug only when public health and safety officials tell you to do so. Start treatment as soon as possible for the best protection. The length of treatment will be determined by public health and safety officials.

If so directed, use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Tell your doctor if your condition lasts or gets worse.

Nausea, vomiting, stomach ache, diarrhea, metallic taste in the mouth, fever, headache, runny nose, sneezing, or acne may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

• burning mouth/throat
• sore teeth/gums
• swelling inside the mouth
• increased saliva
• eye irritation/swollen eyelids
• severe headache
• swelling of the front of the neck/throat (goiter)
• signs of decreased thyroid gland function (such as weight gain, cold intolerance, slow/irregular heartbeat, constipation, unusual tiredness)
• confusion
• numbness/tingling/pain/weakness of the hands/feet

Get medical help right away if you have any very serious side effects, including:

• chest pain
• black stools
• vomit that looks like coffee grounds
• bloody diarrhea

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing
• fever with joint pain

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before taking this medication, tell your doctor or pharmacist if you are allergic to iodine or potassium iodide; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

• bronchitis
• a certain type of skin condition (dermatitis herpetiformis)
• a certain type of blood vessel disease (hypocomplementemic vasculitis)
• any thyroid problems (if you are taking this medication for non-thyroid conditions)
• heart disease
• tuberculosis
• high level of potassium in the blood
• kidney disease
• Addison's disease
• a certain muscle disorder (myotonia congenita)

Caution is advised when this drug is given to newborn babies younger than 1 month old. Repeated dosing increases the risk of blocking thyroid function, possibly affecting the newborn's brain development. Discuss the risks and benefits with the doctor. Treated babies should be given thyroid function tests.

During pregnancy, this medication should be used only when clearly needed. Repeated dosing increases the risk of blocking thyroid function in the unborn baby, possibly causing harm. Discuss the risks and benefits with your doctor.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug are:

• ACE inhibitors (such as captopril, lisinopril)
• angiotensin receptor blockers (ARBs such as losartan, valsartan)
• certain "water pills" (potassium-sparing diuretics such as amiloride, spironolactone, triamterene)
• drospirenone
• eplerenone
• lithium
• drugs that contain potassium (including supplements such as potassium chloride)

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669. Symptoms of overdose may include: stomach pain, nausea/vomiting, severe diarrhea, trouble breathing, weakness.

Do not share this medication with others.

Lab and/or medical tests (such as thyroid function) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light. Do not freeze. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.