Furadantin 25 mg/5 mL oral suspension

The photos shown are samples only

Generic name:
Nitrofurantoin suspension - oral

Pronunciation
(NYE-trow-fyour-AN-toe-in)

Brand name(s)
Furadantin

Nitrofurantoin is an antibiotic used to treat or prevent certain bladder infections. It works by stopping the growth of bacteria.

This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

This medication should not be used in infants younger than 1 month old (see also Precautions section). This drug should not be used to treat infections outside the bladder (including kidney infections such as pyelonephritis or perinephric abscesses).

How to use

Shake the bottle well before each dose. Take this medication by mouth with food as directed by your doctor. This medication is usually taken 4 times daily to treat an infection or once daily at bedtime to prevent infections. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage and length of treatment is based on your medical condition and response to treatment. Children's dosage is also based on weight.

This drug may be mixed into water, juice, milk, or formula to improve the taste. Rinse the mouth after each dose to help prevent temporary staining of the teeth.

Do not use magnesium trisilicate-containing antacids while taking this medication. These antacids can bind with nitrofurantoin, preventing its full absorption into your system.

For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

When taking this medication to prevent infection, take it exactly as directed by your doctor. Do not skip doses or stop taking it without your doctor's approval. Tell your doctor if you notice signs of a bladder infection (such as pain while you are urinating).

If you are taking this medication to treat an infection, continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Tell your doctor if your condition lasts or gets worse.

Side effects

Nausea, vomiting, loss of appetite, or headache may occur. Take this medication with food to help minimize nausea. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may cause your urine to turn dark yellow or brown in color. This is usually a harmless, temporary effect and will disappear when the medication is stopped. However, dark brown urine can also be a sign of rare side effects (liver problems or anemia). Get medical help right away if you notice dark urine along with any of the following symptoms:

nausea/vomiting that doesn't stop
stomach/abdominal pain
yellowing eyes/skin
tiredness
fast/pounding heartbeat

Tell your doctor right away if you have any serious side effects, including:

headaches that are severe or don't go away
eye pain
vision changes
mental/mood changes
new signs of infection (such as sore throat that doesn't go away, fever)
easy bruising/bleeding

Get medical help right away if you have any very serious side effects, including:

numbness/tingling of the hands/feet
unusual muscle weakness

This medication may rarely cause very serious (possibly fatal) lung problems. Lung problems may occur within the first month of treatment or after long-term use of nitrofurantoin (generally for 6 months or longer). Get medical help right away if you develop symptoms of lung problems, including:

cough that doesn't go away
chest pain
shortness of breath/trouble breathing
joint/muscle pain
bluish/purplish skin

This medication may rarely cause a severe intestinal condition due to a bacteria called C. difficile. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop:

diarrhea that doesn't stop
abdominal or stomach pain/cramping
blood/mucus in your stool

If you have these symptoms, do not use anti-diarrhea or opioid products because they may make symptoms worse.

Use of nitrofurantoin for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

rash
itching/swelling (especially of the face/tongue/throat)
severe dizziness
trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking nitrofurantoin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

kidney disease
liver disease (including liver problems caused by nitrofurantoin in the past)
a certain genetic condition (G-6-PD deficiency)
lung disease
numbness/tingling of the arms/legs
vitamin B deficiency
mineral imbalance
blood disorders (such as anemia)
diabetes
ongoing weakness due to long-term disease
certain eye disorders (such as optic neuritis)

Older adults may be at a greater risk for side effects while using this drug, especially nerve, liver or lung problems.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Nitrofurantoin may cause live bacterial vaccines (such as typhoid vaccine) to not work well. Tell your health care professional that you are using nitrofurantoin before having any immunizations/vaccinations.

During pregnancy, this medication should be used only when clearly needed. It must not be used if you are near the end of your pregnancy (38-42 weeks) or at the time of labor and delivery. Doing so may cause a certain blood disorder (hemolytic anemia) in your baby. Discuss the risks and benefits with your doctor.

This medication passes into breast milk and may have undesirable effects on nursing infants younger than 1 month old or those with a certain genetic condition (G-6-PD deficiency). Consult your doctor before breastfeeding.

Drug interactions