Linaclotide - oral
Linaclotide - oral
This medication is not recommended for use in people younger than 18 years. It may cause harm, especially in children younger than 6 years. Talk to your doctor for details.
See also Warning section.
Linaclotide is used to treat certain types of bowel problems (irritable bowel syndrome with constipation, chronic idiopathic constipation). It works by increasing fluid in your intestines and helping speed up movement of food through the gut. Linaclotide may improve stool texture and lessen symptoms such as bloating, abdominal pain/discomfort, straining, and feelings of incomplete bowel movements.
This medication must not be used in children younger than 6 years because of the risk of serious side effects.
Read the Medication Guide provided by your pharmacist before you start taking linaclotide and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth on an empty stomach as directed by your doctor, usually once daily at least 30 minutes before your first meal of the day. Swallow the capsules whole. Do not break or chew the capsules.
If you have trouble swallowing the capsule, it may be opened and the contents mixed in a teaspoonful of applesauce. Swallow the mixture right away, without chewing it. Do not save the mixture for future use.
You may also empty the capsule's content into an ounce (30 milliliters) of water. Swirl the mixture for 20 seconds and drink right away, without chewing it. Add another ounce (30 milliliters) of water to the cup, swirl for 20 seconds and drink right away to get your whole dose. The water mixture may also be given through a tube into the stomach (nasogastric or gastric tube). If you are giving this medication through a tube, ask your health care professional for detailed instructions on how to give it.
The dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.
Tell your doctor if your condition does not improve or if it worsens.
Diarrhea, bloating, gas, or stomach/abdominal pain/discomfort may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Stop taking this medication and tell your doctor right away if you have any serious side effects, including:
In the US -
Before taking linaclotide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
A product that may interact with this drug is:
Do not share this medication with others.
If you miss a dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Store in the original container (tightly closed) at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Information last revised July 2018.
Copyright(c) 2018 First Databank, Inc.