An institutional review board (IRB) is an independent committee made up of medical and nonmedical members, such as physicians, statisticians, and community advocates. It ensures that a clinical trial is ethical and that the rights of study participants are protected.
All institutions that conduct or support biomedical research involving people, by U.S. government regulation, must have an IRB that initially approves and periodically reviews the research.
An IRB reviews and approves protocols, informed-consent forms, physician credentials and eligibility, and other patient materials. The role of an IRB is to work closely with the U.S. Food and Drug Administration (FDA) to make sure that patient safety is the main priority of a clinical trial.
Current as of: December 19, 2018
Author: Healthwise Staff
Medical Review:Adam Husney, MD - Family Medicine & E. Gregory Thompson, MD - Internal Medicine & Kathleen Romito, MD - Family Medicine & Michael S. Rabin, MD - Medical Oncology