Learning About Leukotriene Modifiers

Leukotriene (say "loo-koh-TRY-een") modifiers are medicines used for asthma and seasonal allergies.

They help reduce asthma symptoms. They are not used to treat asthma attacks.

They also reduce allergy symptoms. These include sneezing and a runny or stuffy nose.

• Montelukast (Singulair)
• Zafirlukast (Accolate)
• Zileuton (Zyflo)

• Vomiting.
• Diarrhea.
• A headache.

Call your doctor right away if you or your child has behavior or mood changes while taking montelukast.

• These drugs may help if your asthma is caused by exercise, aspirin, or allergies.
• You may need to have blood tests during the first 6 months of treatment. The tests check for liver damage.
• Take your medicines exactly as prescribed. Call your doctor if you think you are having a problem with your medicine.
• Check with your doctor or pharmacist before you use any other medicines. This includes over-the-counter drugs. Make sure your doctor knows all of the medicines you take. This includes vitamins, herbs, and supplements. Taking some drugs together can cause problems.