Tafenoquine 150 milligram tablet - oral
Tafenoquine 150 milligram tablet - oral
Tafenoquine is used in combination with another medication (such as chloroquine) to treat and prevent the return of malaria. Malaria is caused by infection with a parasite spread by mosquito bite. After they multiply and grow, the parasites infect your red blood cells and cause symptoms of malaria (such as fever, chills, sweating, headache, other flu-like symptoms). This medication works by stopping the growth of the parasite that causes malaria.
Read the Patient Information Leaflet if available from your pharmacist before you start taking tafenoquine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with food as directed by your doctor, usually a one-time dose taken on the first or second day of treatment with other antimalarial medication. The manufacturer directs to swallow this medication whole, and to not break, crush, or chew the tablet before taking it. However, many similar drugs (immediate-release tablets) can be split, crushed, or chewed. Follow your doctor's directions on how to take this medication.
If you vomit within 1 hour after taking your dose, ask your doctor if you should take another dose.
No medication is completely effective in preventing the return of malaria. Malaria treatment works best when it is started early. Tell your doctor if your symptoms do not get better or if they get worse.
Tafenoquine stays in your body a long time, so side effects may be delayed or last longer than expected.
Trouble sleeping, anxiety, or nightmares may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including:
Get medical help right away if you have any very serious side effects, including:
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
In the US -
Before taking tafenoquine, tell your doctor or pharmacist if you are allergic to it; or to chloroquine or primaquine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
Tell your doctor if you are pregnant or plan to become pregnant. Women of childbearing age should have a pregnancy test before taking this medication. You should not become pregnant while using tafenoquine. Tafenoquine may harm an unborn baby. Ask about reliable forms of birth control for 3 months after the dose. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.
It is unknown if this medication passes into breast milk. A blood test to check if your baby has G6PD deficiency should be done before you start breast-feeding. If your baby is G6PD deficient or if the G6PD status is unknown, breast-feeding is not recommended for 3 months after the dose. Consult your doctor before breast-feeding.
This medication can slow down the removal of other medications from your body, which may affect how they work. One example is dofetilide, among others.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Do not share this medication with others.
Lab and/or medical tests (such as G6PD deficiency) should be done before you take this medication. Women of childbearing age should also have a pregnancy test before taking this medication. Keep all medical and lab appointments.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Information last revised January 2019.
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