Factor ix, recombinant, pegylated - injection
Factor ix, recombinant, pegylated - injection
This medication is used to treat and control bleeding episodes in people with little or no factor IX (due to hemophilia B, Christmas disease). Factor IX is a protein normally found in the blood that helps the blood to thicken (clot) and stop bleeding. People with little or no factor IX are at risk for bleeding longer after an injury/surgery or bleeding suddenly (often in the joints/muscle) without an obvious cause. This medication contains a man-made form of factor IX.
This medication is given by injection into a vein over several minutes as directed by your doctor. After first receiving this medication in a hemophilia treatment center or hospital, some people may be able to give it to themselves at home. If your doctor directs you to use this medication at home, read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. Learn all preparation and usage instructions in the product package. Learn how to store and discard medical supplies safely. If you have any questions, ask your health care professional.
The medication in the vial and the supplies that come with the medication should be used only once. Do not reuse. If the medication and the solution used to mix it were refrigerated, bring both to room temperature before combining. After adding the solution to the powder, gently swirl the mixture to completely dissolve the powder. Do not shake. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.
The dosage is based on your medical condition (amount and location of bleeding), weight, and response to treatment.
Tell your doctor right away if your bleeding does not stop or if this medication stops working well.
Swelling, pain, or irritation at the injection site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Tell your doctor right away if you have any serious side effects, including:
This medication may rarely cause blood clots (such as pulmonary embolism, stroke, heart attack, deep vein thrombosis). Get medical help right away if any of these side effects occur:
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
In the US -
Before using factor IX, tell your doctor or pharmacist if you are allergic to factor IX products; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Some products that may interact with this drug are:
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Do not share this medication with others.
Lab and/or medical tests (such as factor IX activity) may be done while you are using this medication. Keep all medical and lab appointments.
If more than one dose is needed, it is important to follow the dosing schedule as directed by your doctor. If you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule. Do not double the dose to catch up.
Store the unmixed product in the refrigerator or at room temperature. If you store it at room temperature, use it within 6 months from the date that you removed it from the refrigerator or before the expiration date on the box, whichever is sooner. Do not put room temperature product back in the refrigerator. Do not freeze. Store the vials in the original box and protect from light. After the powder is mixed into solution, use it within 4 hours and discard any unused portion. Keep all medications away from children and pets.
Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).
Information last revised June 2019.
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