Iron dextran - injection
Dexferrum , INFeD
Iron dextran - injection
Dexferrum , INFeD
Infrequently, iron dextran for injection has caused severe (sometimes fatal) allergic reactions. It should be used only when clearly needed and when a patient is unable to take iron by mouth (oral forms).
Tell your doctor right away if you experience signs of an allergic reaction such as trouble breathing, dizziness, rash, or itchy skin.
This medication is used to treat "iron-poor" blood (anemia) in people who cannot take iron by mouth because of side effects or because their anemia has not been successfully treated by it. Low iron levels can occur when the body can't get enough iron from food (poor nutrition, poor absorption) or when there is a large or long-term blood loss (for example, due to hemophilia, stomach bleeding). It is also used by people who have anemia due to long-term kidney disease.
Iron is an important part of your red blood cells and is needed to carry oxygen in the body.
This medication is usually injected deep into the muscle of the buttock or slowly into a vein as directed by your doctor. When injecting into the buttock, the next injection is given on the opposite side from the last injection.
Before the first full dose, a smaller test dose is given slowly to check for possible allergic effects. If no reaction is seen after one hour, the full dose may be given. You will be checked carefully for reactions by a health care worker each time you are getting the iron.
Iron injections may be given once daily in small doses or as directed by your doctor. Large doses may be given in a solution and injected into a vein over several hours. Some side effects such as dizziness and flushing may be stopped by giving the drug more slowly. The dose and length of treatment is based on your age, weight, condition, and response to therapy. Your doctor will order blood tests to monitor your response.
If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
Flushing, tingling of the hands/feet, shivering, or dizziness may occur. The area around the injection site may be tender, irritated, or discolored (brown). If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
Some people may experience a delayed reaction 1-2 days after their treatment. These side effects usually lessen within 3 to 4 days if the medication was injected into a vein or within 3 to 7 days if the medication was injected into a muscle. Tell your doctor if any of these side effects persist or worsen more than 4 to 7 days after your treatment:
Tell your doctor right away if you have any serious side effects, including:
Get medical help right away if any of these rare but very serious side effects occur:
A very serious allergic reaction to this drug may occur. Get medical help right away if you notice any of the following symptoms of a serious allergic reaction:
In the US -
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Some products that may interact with this drug include:
This medication may interfere with certain laboratory tests (including bilirubin, calcium, and clotting times), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Laboratory and/or medical tests (e.g., complete blood count, iron) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
It is important to maintain a well-balanced diet to ensure adequate intake of iron, vitamins, and minerals. Good sources of iron include meats (especially liver), eggs, raisins, figs, broccoli, Brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Follow any diet recommendations given to you by your doctor.
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule. Do not double the dose to catch up.
Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised February 2019.
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