Nivolumab - injection
Nivolumab - injection
Nivolumab is used to treat cancer. It works by changing the action of your own immune system, directing it to attack cancer cells. Nivolumab belongs to a class of drugs known as monoclonal antibodies.
Read the Medication Guide provided by your pharmacist before you start receiving nivolumab and each time you get a treatment. If you have any questions, ask your doctor or pharmacist.
This medication is given by a health care professional. It is injected slowly into a vein over 30 minutes. It is given as directed by your doctor, usually once every 2 to 4 weeks.
Infusion reactions may happen while you are receiving the drug. Tell your doctor right away if you have symptoms such as fever, chills, flushing, dizziness, or fainting.
The dosage is based on your medical condition, weight, and response to treatment. Your doctor may stop your treatment for some time if you get serious side effects. Your doctor may also prescribe another medication (a corticosteroid such as prednisone) to help treat side effects of this medication.
Diarrhea may occur. If this effect persists or worsens, tell your doctor or pharmacist promptly.
People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.
Tell your doctor right away if you have any serious side effects, including:
Nivolumab may cause hormone gland problems (such as thyroid, pituitary, adrenal, pancreas). Your body could make too much or too little hormone. Tell your doctor right away if you have any symptoms such as:
Get medical help right away if you have any very serious side effects, including:
Nivolumab can commonly cause itching or a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Therefore, get medical help right away if you develop any rash or itching.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
In the US -
Before using nivolumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using nivolumab. Nivolumab may harm an unborn baby. Ask about reliable forms of birth control while using this medication and for 5 months after stopping treatment. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.
It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug and for 5 months after stopping treatment is not recommended. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Lab and/or medical tests (such as liver/kidney/thyroid function, blood sugar) should be done before and during treatment with this medication. Keep all medical and lab appointments. Consult your doctor for more details.
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule.
Not applicable. This medication is given in a hospital or clinic and will not be stored at home.
Information last revised May 2019.
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