Letermovir - oral
Letermovir - oral
This medication is used to prevent disease caused by a virus called cytomegalovirus (CMV) in people who have received a bone marrow transplant. CMV disease can lead to serious infections in the body, including an infection in the eye, called CMV retinitis, that can cause blindness. Letermovir is an anti-viral drug. It works by stopping the growth of the virus.
Read the Patient Information Leaflet if available from your pharmacist before you start taking letermovir and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food, as directed by your doctor, usually once daily. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Swallow the tablet whole. Do not crush or chew because the drug has a bitter taste.
For the best effect, take this medication at evenly spaced times. To help you remember, take this medication at the same time every day.
Continue to take this medication until the full prescribed amount is finished. Stopping the medication too early may result in an infection.
Nausea, diarrhea, vomiting, swelling ankles/feet, cough, or headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Tell your doctor right away if you have any serious side effects, including:
In the US -
Before taking letermovir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
This medication can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include ergot alkaloids (such as ergotamine, dihydroergotamine), flibanserin, pimozide, certain statin drugs (such as pitavastatin, simvastatin), among others.
Other medications can affect the removal of letermovir from your body, which may affect how letermovir works. Examples include rifampin, among others.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Do not share this medication with others.
This medication has been prescribed for your current condition only. Do not use it later to prevent another infection unless your doctor tells you to.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Store at room temperature away from light and moisture in the original package. Do not store in the bathroom. Keep all medications away from children and pets.
Information last revised December 2017.
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