Elotuzumab - injection
Elotuzumab - injection
Elotuzumab is used to treat a certain type of cancer (multiple myeloma).
Read the Patient Information Leaflet if available from your pharmacist before you start using elotuzumab and each time you receive the medication. If you have any questions, ask your doctor or pharmacist.
This medication is given by injection into a vein by a health care professional. It is given as directed by your doctor, usually once a week for the first 8 weeks. After that it is usually given once every 2 or 4 weeks. The dosage is based on your weight and other medications you are taking.
To help prevent side effects (infusion reactions), your doctor may direct you to use other medications before you receive this medication. Use these additional medications exactly as directed by your doctor. Tell your doctor right away if you have any symptoms of infusion reactions such as fever, chills, dizziness, chest discomfort, and slow heartbeat.
See also How to Use section.
Loss of appetite, weight loss, diarrhea, constipation, headache, or tiredness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including:
This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough).
People who are treated with this medication may rarely get other cancers (such as skin cancer). Consult your doctor for more details.
In the US -
Before using elotuzumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Elotuzumab can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.
Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.
Elotuzumab, when used in combination with lenalidomide or pomalidomide, must not be used during pregnancy. The combination may cause harm (possibly death) to an unborn baby. Two reliable forms of birth control (such as condoms, birth control pills) must be used whenever at least one sexual partner is using these medicines together. Males using these medications must always use a condom during sexual activity. If you or your partner become pregnant, or if you think you or your partner may be pregnant, tell your doctor right away.
It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug and lenalidomide or pomalidomide is not recommended. Consult your doctor before breast-feeding.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Lab and/or medical tests (such as kidney/liver function, complete blood count, blood mineral levels, blood pressure, heart rate) should be done while you are using this medication. Keep all medical and lab appointments. Consult your doctor for more details.
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule.
Not applicable. This medication is given in a clinic or doctor's office and will not be stored at home.
Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).
Information last revised January 2019.
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