Selexipag - oral
Selexipag - oral
Selexipag is used to treat high blood pressure in the lungs (pulmonary arterial hypertension-PAH). It is used to help slow down worsening of PAH and to decrease the chance of needing treatment in a hospital. Selexipag works by making it easier for blood to flow through the arteries in your lungs. This effect helps increase your ability to exercise.
Read the Patient Information Leaflet if available from your pharmacist before you start taking selexipag and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually twice daily. Taking this medication with food may lessen stomach upset.
The manufacturer directs not to split, crush, or chew the tablet before taking it. However, many similar drugs (immediate-release tablets) can be split, crushed, or chewed. Follow your doctor's directions on how to take this medication.
The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
Tell your doctor if your condition does not get better or if it gets worse.
Headache, nausea, vomiting, diarrhea, loss of appetite, flushing, jaw pain, joint/muscle pain, or pain in your arms or legs may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
In the US -
Before using selexipag, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
Other medications can affect the removal of selexipag from your body, which may affect how selexipag works. An example is gemfibrozil.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Do not share this medication with others.
If you miss a dose, take it as soon as you remember. If it is within 6 hours until the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up. If you miss 3 or more days of medication, ask your doctor how to safely restart selexipag.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Information last revised July 2017.
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