Galsulfase - injection
Galsulfase - injection
Galsulfase is used to treat a certain rare genetic problem (Maroteaux-Lamy syndrome - MLS). Galsulfase replaces a certain natural substance that is missing in people with MLS.
This medication improves how far you can walk and the number of stairs you can climb up. Galsulfase does not correct the genetic problem, and treatment must be continued for life.
This medication is given slowly into a vein as directed by your doctor, usually over 4 hours once a week. The dosage is based on your weight, medical condition, and response to treatment.
If you are using this medication at home, galsulfase will be shipped to your home. A nurse will come to your home to give you the treatment and to monitor you afterward. Do not shake the medication. Galsulfase should be colorless or pale yellow. Before using, check this product visually for particles or discoloration. If either is present, do not use it. Discard any unused prepared medication. Do not save for later use. Learn how to store and discard medical supplies safely.
Galsulfase may cause side effects (such as fever, chills, rash, shortness of breath, nausea/vomiting, increased blood pressure, headache, chest pain, dizziness, weakness/tiredness, joint pain, flushing, coughing) while it is being given and for a short time after the infusion has stopped. Your doctor may decide to stop or slow down the medication infusion for a while if this happens. Tell your healthcare professional right away if you have any of these symptoms. Your doctor may direct you to take other medications (such as antihistamines, drugs for fever, or corticosteroids such as prednisone) to treat your reaction and before your next treatment(s) to prevent these reactions from happening again.
Use this medication regularly to get the most benefit from it. To help you remember, use it on the same day each week.
Tell your doctor if your condition gets worse.
See also How to Use section.
Ear pain, eye redness/itching/discharge, or stomach/abdominal pain may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Tell your doctor right away if you have any serious side effects, including:
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
In the US -
Before using galsulfase, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Do not share this medication with others.
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor to establish a new dosing schedule. Do not double the dose to catch up.
Before mixing, store the vial in the refrigerator. Protect from light and freezing.
Once it has been mixed, consult the product instructions and your pharmacist for storage details. Discard any unused portion. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised November 2016.
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