Plasma exchange (plasmapheresis)

Skip Navigation

Plasma exchange (plasmapheresis) is a procedure done to remove part of a person's blood that may be the cause of a disease. In plasma exchange, whole blood is withdrawn and the liquid portion (plasma) is separated from the red and white blood cells and replaced with a saline and albumin (protein) solution.

Plasma exchange requires access to a large vein. The procedure may be more dangerous if it is performed on older adults or people with heart disease.

The Health Encyclopedia contains general health information. Not all treatments or services described are covered benefits for Kaiser Permanente members or offered as services by Kaiser Permanente. For a list of covered benefits, please refer to your Evidence of Coverage or Summary Plan Description. For recommended treatments, please consult with your health care provider.