Hepatitis B Vaccine for Children: Care Instructions

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Overview

The hepatitis B vaccine protects against infection with the hepatitis B virus. A hepatitis B infection can damage the liver and lead to liver cancer.

Babies and children may get the hepatitis B vaccine. Your child’s doctor can help you decide the best vaccination schedule for your child based on current recommendations and your child’s risk.

If your child is exposed to hepatitis B before getting the vaccine, your child may need a hepatitis B immune globulin (HBIG) shot. This gives instant protection. The HBIG shot will prevent infection until the hepatitis B vaccine takes effect.

The vaccine may cause pain at the injection site. It can also cause a mild fever for a short time. Your child should not get this vaccine if they are allergic to baker's yeast. This is the kind of yeast used to make bread. Your child should not get a second or third dose if they had a bad reaction to the first shot.

Follow-up care is a key part of your child's treatment and safety. Be sure to make and go to all appointments, and contact your doctor if your child is having problems. It's also a good idea to know your child's test results and keep a list of the medicines your child takes.

How can you care for your child at home?

  • You may give your child acetaminophen (Tylenol) or ibuprofen (Advil, Motrin) for pain or fussiness, to help lower a fever, or if the area where the shot was given is sore. Do not use ibuprofen if your child is less than 6 months old unless the doctor gave you instructions to use it. Be safe with medicines. Read and follow all instructions on the label.
  • Do not give a child two or more pain medicines at the same time unless the doctor told you to. Many pain medicines have acetaminophen, which is Tylenol. Too much acetaminophen (Tylenol) can be harmful.
  • Do not give aspirin to children and teens. It has been linked to Reye syndrome, a rare but serious illness.
  • Put ice or a cold pack on the sore area for 10 to 20 minutes at a time. Put a thin cloth between the ice and your child's skin.

When should you call for help?

Call 911 anytime you think your child may need emergency care. For example, call if:

  • Your child has a seizure.
  • Your child has symptoms of a severe allergic reaction. These may include:
    • Sudden raised, red areas (hives) all over the body.
    • Swelling of the throat, mouth, lips, or tongue.
    • Trouble breathing.
    • Passing out (losing consciousness). Or your child may feel very lightheaded or suddenly feel weak, confused, or restless.
    • Severe belly pain, nausea, vomiting, or diarrhea.

Contact your doctor now or seek immediate medical care if:

  • Your child has symptoms of an allergic reaction, such as:
    • A rash or hives (raised, red areas on the skin).
    • Itching.
    • Swelling.
    • Mild belly pain or nausea.
  • Your child has a high fever.
  • Your child cries in a different manner or for an unusual length of time.

Watch closely for changes in your child's health, and be sure to contact your doctor if your child has any problems.

Where can you learn more?

Go to http://www.healthwise.net/patientEd

Enter A314 in the search box to learn more about "Hepatitis B Vaccine for Children: Care Instructions".

Current as of: April 1, 2026

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

Current as of: April 1, 2026

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

The Health Encyclopedia contains general health information. Not all treatments or services described are covered benefits for Kaiser Permanente members or offered as services by Kaiser Permanente. For a list of covered benefits, please refer to your Evidence of Coverage or Summary Plan Description. For recommended treatments, please consult with your health care provider.