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Coombs Test: About This Test

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What is it?

A Coombs test is a type of antibody test. It checks your blood for certain antibodies that attack red blood cells. Antibodies are proteins made by the immune system. Normally, antibodies bind to foreign substances, such as bacteria and viruses, and cause them to be destroyed.

Why is this test done?

This test is used to:

  • Test blood before a transfusion.
  • Find antibodies caused by disease or a blood transfusion.
  • Check a newborn baby with Rh-positive blood whose mother has Rh-negative blood.
  • Check to see if a pregnant woman has Rh-positive or Rh-negative blood.

How do you prepare for the test?

In general, there's nothing you have to do before this test, unless your doctor tells you to.

How is the test done?

A health professional uses a needle to take a blood sample, usually from the arm.

How long does the test take?

The test will take a few minutes.

What happens after the test?

  • You will probably be able to go home right away.
  • You can go back to your usual activities right away.

Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to keep a list of the medicines you take. Ask your doctor when you can expect to have your test results.

Where can you learn more?

Go to http://www.healthwise.net/patientEd

Enter Y320 in the search box to learn more about "Coombs Test: About This Test".

Current as of: April 30, 2024

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

Current as of: April 30, 2024

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

The Health Encyclopedia contains general health information. Not all treatments or services described are covered benefits for Kaiser Permanente members or offered as services by Kaiser Permanente. For a list of covered benefits, please refer to your Evidence of Coverage or Summary Plan Description. For recommended treatments, please consult with your health care provider.