propantheline 15 mg tablet

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Medication name

Generic name:
Propantheline - oral

Pronunciation
(proe-PAN-the-leen)

Brand name(s)
Pro-Banthine

Uses

Propantheline is used with other medications to treat peptic ulcers. It works by decreasing the release of acid in the stomach.

Other uses

This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This drug may also be used for extra stomach acid (such as Zollinger-Ellison syndrome) or certain bowel disorders (such as irritable bowel syndrome). For bowel disorders, the medication works by decreasing the movement of the stomach/intestines.

How to use

Take this medication by mouth, usually 30 minutes before each meal and at bedtime or as directed by your doctor.

Dosage is based on your medical condition and response to therapy.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Inform your doctor if your condition persists or worsens.

Side effects

Dry mouth, decreased sweating, dizziness, drowsiness, blurred vision, widened pupils, nausea/vomiting, or constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur:

  • mental/mood changes
  • eye pain/pressure
  • fast/pounding heartbeat
  • difficulty urinating

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking propantheline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • glaucoma
  • myasthenia gravis
  • movement/blockage disorders of the stomach/bowels (such as paralytic ileus, pyloroduodenal stenosis, achalasia, intestinal atony)
  • difficulty urinating (for example, due to prostatic hypertrophy)
  • overactive thyroid (hyperthyroidism)
  • liver disease
  • kidney disease
  • high blood pressure
  • heart/blood vessel disease (such as congestive heart failure, coronary artery disease, tachycardia)
  • esophagus problems (such as GERD)
  • nerve disorders (such as autonomic neuropathy)
  • diarrhea
  • breathing problems (such as asthma)
  • ulcerative colitis

Before having surgery, tell your doctor or dentist that you are using this medication.

This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

This medication can decrease sweating. To prevent heatstroke, avoid becoming overheated in hot weather, in saunas, and during exercise/other strenuous activities.

Caution is advised when using this drug in the elderly because they may be more sensitive to the side effects.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include:

  • antispasmodics (e.g., dicyclomine)
  • belladonna alkaloids (e.g., scopolamine, atropine)
  • certain antiarrhythmic drugs (e.g., quinidine)
  • certain drugs for Parkinson's disease (e.g., benztropine, trihexyphenidyl)
  • corticosteroids (e.g., prednisone)
  • digoxin (slow-dissolving type)
  • drugs which depend on stomach acidity (e.g., ketoconazole)
  • MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine)
  • phenothiazines (e.g., chlorpromazine)
  • potassium tablets/capsules
  • pramlintide
  • tricyclic antidepressants (e.g., amitriptyline)

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: mental/mood changes, fainting, muscle weakness, fast/irregular heartbeat, hot/dry skin, trouble breathing.

Notes

Do not share this medication with others.

Missed dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Important note

HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Information last revised February 2019.

Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc., 2019. This copyrighted material has been downloaded from a licensed data provider.

The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment.